Syndromic Multiplex Polymerase Chain Reaction (mPCR) Testing and Antimicrobial Stewardship: Current Practice and Future Directions

The polymerase chain reaction: current and future clinical applications.

The polymerase chain reaction has undergone rapid improvement since its initial development, such that the technique currently permits rapid, accurate, predictive tests to be made in the field of prenatal diagnosis and has greatly aided forensic medicine. It is anticipated that the polymerase chain reaction will also facilitate advances in other fields, in particular preimplantation diagnosis, ...

Antimicrobial Stewardship with Intravenous to Oral Conversion and Future Directions of Antimicrobial Stewardship

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Editorial Antimicrobial stewardship (ASP) as defined by the Infectious Diseases Society of America (IDSA), the Society for Healthcare Epidemiology of America (SHEA), and the Pediatric Infectious Diseases Society (PIDS) are " coordinated interventions designe...

Impact of Multiplex Polymerase Chain Reaction Technology with Antimicrobial Stewardship Interventions in the Management of Patients with Positive Blood Cultures

Rfbo157 by Multiplex Polymerase Chain Reaction

A rapid method for detection of Escherichia coli O157: H7 using multiplex PCR was developed. Two oligonucleotide primer pairs were used for simultaneously detection of vt encoding verotoxin genes for virulence factor and rfbO157 encoding the O-antigen specific for E. coli O157: H7. Multiplex PCR generated two products of 215 bp and 420 bp for vt and rfbO157, respectively. Multiplex PCR detected...

Record Linkage: Current Practice and Future Directions

Record linkage is the task of quickly and accurately identifying records corresponding to the same entity from one or more data sources. Record linkage is also known as data cleaning, entity reconciliation or identification and the merge/purge problem. This paper presents the “standard” probabilistic record linkage model and the associated algorithm. Recent work in information retrieval, federa...